Enzyme Research 是一家擁有超過25年的酶研究的實驗室，生產和開發多種用于基本凝血研究的多種酶和輔因子。在過去的十年Enzyme Research Laboratories為科學家參與止血和血栓形成的研究提供了寶貴支持。Enzyme Research通過不斷追求產品的zui高品質，贏得了世界各地凝血研究實驗室的信任。

Enzyme Research Laboratories為生物技術公司,制藥行業、醫院和大學的研究實驗室提供用于的純化抗凝因子。除了其制造能力，Enzyme Research Laboratories也創新研發領域中的血液凝固技術。

Human Factor αXIIa

HFXIIa 1212a             Human Factor αXIIa 
                              （Activated Hageman Factor）

Human Factor α-XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system. Human Factor XII and prekallikrein are thought to be involved in a reciprocal activation mechanism in which Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to XIIa. Factor XIIa activates Factor XI to XIa thereby triggering the Contact Factor cascade. ERL offers Factor α-XIIa which is activated by the autoactivation process with Dextran Sulfate and re-purified to remove the activator. The protein purity is determined by SDS-PAGE and activity is determined via clotting assay.

Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3
*Extinction Coefficient （1%） = 14.1
Molecular Weight = 80,000 daltons

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